On "The Grid" (2004)'s: "What I love about the script is that it shows many points of view instead of just one."

On September 11: "Everyone reacts differently. My reaction was I needed to go down there to help. Friends I had couldn't watch the television any more, couldn't go down there. But I needed to do whatever I could. And I did go down there and help. I cooked for the guys. I visited sick people. I felt, I'm from New York and it's my community and it's what I know and I wouldn't have wanted to be anywhere else."

On Steven Seagal, with whom she worked with on the movie Out for Justice (1991): "His trailer is around the corner from mine on the Warner Bros. lot, and I was walking by recently and he said, 'Margulies, come over here and show me some respect!' He's not someone I keep in touch with."